Dear all,

Please find below the advertisement for a PhD position in our research group:

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 PhD position in Structural Biology at JGU/IMB Mainz, Germany

 A PhD position is available in the group of Eva Wolf at the Johannes Gutenberg 
University
(JGU) and the Institute of Molecular Biology (IMB) in Mainz, Germany. Research 
in the Wolf
group is focused on the structural, biochemical and biophysical analysis of 
proteins involved
in circadian regulation (e.g. Czarna et al, Cell 2013; Schmalen et al, Cell 
2014). To elucidate
the molecular mechanisms underlying circadian (day-time dependent) gene 
regulation and
its adaptive evolution, the PhD student will structurally and functionally 
characterize circadian
clock proteins of various organisms. He/she will apply a wide range of 
techniques including
recombinant protein expression (E.coli, insect cells), protein purification, 
X-ray crystallography,
biochemical and biophysical protein interaction studies and molecular biology 
to understand
how evolution engineers the 3D-structure, activity and molecular interactions 
of clock proteins
to tune their roles in gene regulation. Within collaborations, she/he will also 
analyze the
molecular interactions, functional activities and evolution of clock proteins 
using cell-based
approaches as well as behavioral and phylogenetic studies.
The project will be performed within a new DFG funded research training group 
(RTG) on
“Gene regulation in 
evolution<https://www.imb.de/about-imb/joint-research-initiatives/genevo/><https://www.imb.de/about-imb/joint-research-initiatives/genevo/>”,
 which enables extensive interdisciplinary collaborations and
networking.  Candidates with a strong interest in structural biology, protein 
biochemistry,
biophysics, protein structure-function relationship and evolutionary biology 
and a significant
previous exposure to these research areas during their master education are 
encouraged to apply.
The prospective PhD student will also be affiliated with IMB’s International 
PhD program (IPP)
and must have a good command of English. The Wolf group is currently located at 
the IMB
(www.imb.de<http://www.imb.de>).

PhD candidates must officially apply via the International PhD Programme (IPP, 
www.imb.de/PhD<http://www.imb.de/PhD>).

The deadline for registration at the IPP is May 22nd 2019.

Informal enquires should be addressed to Eva Wolf 
(evawo...@uni-mainz.de<mailto:evawo...@uni-mainz.de>).


With best regards,

Eva

-----------------------------------------

Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz
Ackermannweg 4
55128 Mainz, Germany
evawo...@uni-mainz.de<mailto:evawo...@uni-mainz.de>
https://www.imb.de/research/wolf/research/




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