Honestly, as a Zugreister to Bavaria and now living in a Sausage Diaspora (by Bavarian standards), I would take any sausage available.
Educational Sausages might be the way to go. You could ask a Sausage Modeler who previously participated in a Sausage-CASP competition to reach out to the authors so he/she can compare his Sausage model with the true and only Sausage. May the Sausage be with you V <- Spock greeting Jürgen > On Apr 7, 2020, at 12:05 PM, Schreuder, Herman /DE > <herman.schreu...@sanofi.com> wrote: > > Dear Frank, > > here I disagree. I think it is bad practice to complain to the editors or > start naming and shaming before asking the authors first. Only if they do not > want to cooperate, it would be time to bring the flame-throwers in position. > > However, I think the situation is more subtle and that that is the reason > Artem wrote his email: He wants the data, but does not want to reveal his > identity to his competitors, who apparently made a significant effort not to > reveal any useful details. > > Here I would let me guide by the (perceived) commercial interest: if it is > not gigantic, then I would contact the authors to prevent a wasteful > duplication of research efforts. > If there is a significant commercial interest, it would probably be better > not to contact them and go the hard way of solving the structure yourself. A > thing to consider is also what would happen if the authors still would > refuse: they know the identity of the competitor and you still do not have > the data. > > An alternative may be to ask an academic friend who also works on sausage > esterases to inquire with the authors… > > Good luck with your decision! > Herman > > Von: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK > <mailto:CCP4BB@JISCMAIL.AC.UK>> Im Auftrag vonFrank von Delft > Gesendet: Dienstag, 7. April 2020 17:19 > An: CCP4BB@JISCMAIL.AC.UK <mailto:CCP4BB@JISCMAIL.AC.UK> > Betreff: [EXTERNAL] Re: [ccp4bb] on-topic: your opinions requested! > > EXTERNAL : Real sender is owner-ccp...@jiscmail.ac.uk > <mailto:owner-ccp...@jiscmail.ac.uk> > > > Write to the editor - that's their job. > > Though they may also see it as their job to ignore emails like yours because > that's far easier than dealing with them. > > Alternatively, go the Rupp Route: Name and Shame! ;) > > > On 07/04/2020 16:08, Artem Evdokimov wrote: > Dear CCP4ers, > > I would like to solicit your thoughts on the following (this is a real > situation, but salient details are changed): > > Imagine that you're an industrial scientist in a small company, working on > the Bavarian Sausage (Weisswurst) Esterase project. The overall structure is > previously unknown, with no good homologs in the PDB, trying to model is "OK > not great" so the structure is really needed... > > Then, you find an article from a large commercial competitor, that somehow > managed to solve the Stadtwurst (Saxony Sausage) Esterase structure (which is > a very close homolog to the one you need!). > > Sounds good - but as you read the paper you realize that the authors managed > to find a journal that allowed them to publish their work without disclosing > neither the coordinates of the model, nor even the crystallization conditions > of the protein - all that's available is a tantalizing still picture of the > active site in surface mode, with a ball-and-stick ligand positioned such > that it is impossible to say what it interacts with. > > So you sit and ponder - whether to write to the Editor, or maybe to contact > the authors directly (but then they would know that you're working on this, > which is not necessarily great since you're competing), or to just buck up > and do the structure on your own (which feels a bit wasteful). Then, you > realize that your friends at CCP4 have a lot of wisdom to offer, so you sit > down and pen an email... > > Any thoughts? > > Artem > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > <https://urldefense.proofpoint.com/v2/url?u=https-3A__www.jiscmail.ac.uk_cgi-2Dbin_webadmin-3FSUBED1-3DCCP4BB-26A-3D1&d=DwMFaQ&c=Dbf9zoswcQ-CRvvI7VX5j3HvibIuT3ZiarcKl5qtMPo&r=HK-CY_tL8CLLA93vdywyu3qI70R4H8oHzZyRHMQu1AQ&m=yyLzWvA2WqYlYHjvwWG6lk3OIm5wwZN_UsYlNbf8Meo&s=zldJ57kosENgJpj99VYugwSVD8wrOzyvCgE4aQH58wc&e=> > > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > <https://urldefense.proofpoint.com/v2/url?u=https-3A__www.jiscmail.ac.uk_cgi-2Dbin_webadmin-3FSUBED1-3DCCP4BB-26A-3D1&d=DwMFaQ&c=Dbf9zoswcQ-CRvvI7VX5j3HvibIuT3ZiarcKl5qtMPo&r=HK-CY_tL8CLLA93vdywyu3qI70R4H8oHzZyRHMQu1AQ&m=yyLzWvA2WqYlYHjvwWG6lk3OIm5wwZN_UsYlNbf8Meo&s=zldJ57kosENgJpj99VYugwSVD8wrOzyvCgE4aQH58wc&e=> > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > <https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
