Hello,

I just tested some structural biology programs on my MacMini with M1 chip (base 
model, MacOS 11.0.1). After installing Xcode command line tools 12.2 and 
Xquartz 2.7.11, open source pymol 2.4.0 (via homebrew), coot 0.8.9.3 (W. 
Scott's binary) and UCSF chimeraX 1.1 (official dmg) are all working and 
operations such as dragging, zooming with map seem to be quite fast. There was 
a short delay when starting the program and I have heard that this is typical 
when rosetta 2 is called.

Below is a brief pymol rendering benchmark for the same figure. MacMini M1 
behaves quite reasonably. The purpose is merely to compare the performance of 
my devices so I apologise for the limited data available ;-)

MacMini M1 8 core: 17.2 frames/ h
MacMini 2018 (i5 3.0 GHz) 6 core: 13.0 frames/ h
MacBook Pro 2012 (i7 2.16 GHz) 8 core: 6.4 frames/ h
CentOS7 (i7 3.2 GHz desktop) 12 core: 13.8 frames/ h




Fig. 1: Open source pymol 2.4.0 starting message from MacMini M1 (upper panel) 
and MacMini 2018 (lower panel).


Greetings,

Wei-Chun

—

Dr. rer. nat. Wei-Chun Kao
[email protected] 
<mailto:[email protected]>
TEL: +49-761-203-5277 <tel:%2B49-761-203-5277>
orcid.org/0000-0001-8687-6334 <http://orcid.org/0000-0001-8687-6334>            
                                

Institute for Biochemistry and Molecular Biology
AG Carola Hunte
Albert-Ludwigs-Universitaet Freiburg
Stefan-Meier-Str. 17
D-79104 Freiburg im Breisgau
Germany

> On 11. Nov 2020, at 10:21, Antony Oliver <[email protected]> wrote:
> 
> Perhaps this is a little too soon, but does anyone know if the new M1 
> system-on-a-chip will continue to run XQuartz/X11 + the CCP4 program suite + 
> other crystallography / EM software? Will CCP4 continue to support the 
> platform?
> 
> (a quick check of the GitHub page indicates that there is already an ARM64 
> implementation of XQuartz)
> 
> I am not in a rush to purchase the newly announced computers, but am keen to 
> understand if we are going to need to future-proof ourselves when the entire 
> family moves over to the new hardware.
> 
> With thanks,
> 
> Antony.
> 
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