Dear colleagues,

Prof Teresa Carlomagno has recently joined the School of Biosciences at the 
University of Birmingham and is in the process of establishing a new research 
group in integrated structural biology. Part of that group is the position of a 
Research Associate position described below.


Full details can be found at: 
https://www.jobs.ac.uk/job/CKC707/research-associate


For informal inquiries, please contact Teresa directly at 
t.carloma...@bham.ac.uk.


Thank you.


Klaus


----------------------------


Research Associate
School of Biosciences
College of Life and Environmental Sciences

Location: University of Birmingham, Edgbaston, Birmingham UK


Full Time FTC for 5 years

Closing date – 30.11.2021



Role/Project Background
The research group to which the post is associated uses integrative structural 
biology to understand functional mechanisms of proteins, nucleic acids and 
their complexes. The Research Associate will express and purify functional 
proteins, produce nucleic acids either by in vitro transcription or chemical 
synthesis, reconstitute large biomolecular particles from recombinant material, 
study the biomolecular complexes with biophysical and biochemical experiments 
and establish functional tests in vitro. The material produced and studied by 
the Research Associate will then be used for structural biology experiments. 
The day-to-daywork includes cloning, bacterial cell culture, protein expression 
and purification, RNA transcription and purification, RNA and protein 
engineering, biophysical studies of biomolecules and of their mutual 
interactions, for example through Isothermal Titration Calorimetry, Multiple 
Angle Light Scattering and Electrophoretic Mobility Assays. In addition, the RA 
will help with laboratory management tasks.


Main duties

  *   •       Collect research data; this may be through a variety of research 
methods, such as scientific experimentation (as described above) and literature 
reviews
  *   •       Analyse research data as directed
  *   •       Present research outputs, including drafting academic 
publications or parts thereof, for example at seminars and as posters
  *   •       Develop or adapt techniques, models and methods
  *   •       Provide guidance as required to support staff and any students 
who may be assisting with research
  *   •       Deal with problems that may affect the achievement of research 
objectives and deadlines
  *   •       Carry out administrative tasks related directly to the delivery 
of the research
  *   •       Promote equality and values diversity acting as a role model and 
fostering an inclusive working culture

Person Specification

•      Degree or equivalent in Biochemistry, Biophysics or Molecular Biology

•      Proficiency in protein recombinant expression and purification and/or in 
RNA synthesis and purification

•      Practical experience in a biochemical laboratory

•      Experience in some of the biophysical techniques mentioned above

•      Skills in analysing data

•      Ability to analyse information and communicate effectively

•      Ability to access and organise resources successfully

•      Knowledge of the protected characteristics of the Equality Act 2010, and 
how to actively ensure in day-to-day activity in own area that those with 
protected characteristics are treated equally and fairly


=======================================================
Klaus Fütterer, PhD
Reader in Structural Biology


School of Biosciences
LES College                                            Email: 
k.futte...@bham.ac.uk
University of Birmingham                         Phone: +44 - 121 - 414 5895
Birmingham, B15 2TT, UK                        (voice mail messages will 
forward to my email inbox)

My normal working hours are Mon - Fri 8.30 - 5.30 pm.


=======================================================

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