I don't know for sure, but I think the -origin-hand thing would be for heavy 
atom work where both enantiomers of the solution can fit the data. Cheers, 
Jon.C.

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-------- Original Message --------
On 18 Mar 2022, 04:02, 付兴科_201928000807036 wrote:

> Dear Colleagues,
>
> In cysmmatch of CCP4, there is a keyworded input,“-origin-hand”. The 
> resolution with "-origin-hand" is very different from the resolution without 
> "-origin-hand". What's the mean of "origin shif" ? How does it work?
> The reference page is <https://www.ccp4.ac.uk/html/csymmatch.html>.
>
> I'm looking forward to your reply.
>
> Regards
>
> Best wishes,
>
> Fu Xingke
>
> Institute of Physics CAS
>
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