**
*Dear colleagues,*
*
We have expanded the superposition process at the PDBe-KB aggregated
views of proteins to allow superposition of the predicted model from the
AlphaFold Protein Structure Database (AlphaFold DB). This new feature
loads the model from AlphaFold DB on demand and superposes it to the
equivalent PDB structures, using the superposition functionality through
the Mol* molecular viewer. This allows easy comparison of the different
conformational states of a given protein in the PDB with the models
predicted in AlphaFold DB, to identify if the predicted model represents
a specific conformational state.
You can view the structure superposition for a specific protein (per
UniProt accession) at the PDBe-KB aggregated views of proteins
(pdbekb.org/protein). The superposition can be accessed from the Summary
or Structures tabs using the green buttons labelled ‘3D view of
superposed structures’.
Read more at
https://www.ebi.ac.uk/pdbe/news/compare-experimental-models-pdb-alphafold-models-pdbe-kb
Kind Regards,
*Deborah Harrus
--
-------------------------------------------------------------------
Deborah Harrus, Ph.D.
Lead Annotator
PDBe - Protein Data Bank in Europe
European Bioinformatics Institute (EMBL-EBI)
European Molecular Biology Laboratory
Wellcome Trust Genome Campus
Hinxton
Cambridge CB10 1SD UK
http://www.PDBe.org
-------------------------------------------------------------------
########################################################################
To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1
This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list
hosted by www.jiscmail.ac.uk, terms & conditions are available at
https://www.jiscmail.ac.uk/policyandsecurity/
