Just a reminder that the applications are still open for this position. On Mon, 31 Oct 2022, 15:12 Misba Ahmad <misba.ah...@gmail.com> wrote:
> ZoBio (www.zobio.com) was founded in 2004 and is located in Leiden, > Netherlands. We offer innovative research services in the field of > small-molecule drug discovery to the pharmaceutical and biotech industries. > Our international team of 40 people covers five fields of expertise: > Protein Sciences, Assay Development and Screening, Structural Biology, > Medicinal Chemistry, and Data and Information Sciences. > > We are looking to strengthen our Structural Biology team with an > enthusiastic scientist with a track record in protein X-ray > crystallography. The structural biology team plays a critical role in > supporting our clients’ drug discovery programs by providing structural > insights into protein-ligand complexes by both NMR spectroscopy and X-ray > crystallography. Our crystallization laboratory is equipped with > state-of-the-art liquid handlers and automated imagers, and we have regular > access to the main European synchrotrons. The team is involved in many > projects with challenging targets and engaged in exploring innovative > workflows. > > It is fully expected that the successful candidate will become a permanent > and integral member of the ZoBio team after an initial 12-month contract. A > tailored remuneration package will be proposed in line with individual > qualifications and experience. The position is immediately available; the > evaluation and assessment of candidates will run until the position is > filled. > > *TASKS & RESPONSIBILITIES* > > As a member of the Structural Biology group, you will work on site in the > laboratory primarily to support crystallization and structure determination > of protein-ligand complexes. You will work with minimal supervision but in > a highly collaborative environment within the Structural Biology group and > will effectively cooperate on a per-project basis with other research > groups at ZoBio. Your role will require working simultaneously on multiple > projects in a rapidly evolving environment. You will: > > Provide input to research projects: > > - Design and implement (co-) crystallization and soaking strategies > utilizing automation and robotics > - High-throughput and -quality structure elucidation and > interpretation of biological macromolecules in complexes with small > molecules of interest > - Troubleshoot proactively various challenges relating to protein > crystallization > - Perform experiments with deadlines > - Report project results in an accurate and concise manner, both > verbally and written > - Keep up to date with relevant literatures and developments in the > field of protein crystallography > > Organize logistics, planning and quality control for research projects: > > - Contribute to the overall quality control process of data that is > generated by the group members > - Control the integrity of data imported in project databases > - Develop innovative approaches to protein crystallization and/or > structure determination, including evaluation of new technologies that > support and improve the workflow > - Share knowledge, observations, and insights within the group and > ZoBio to improve quality and efficiency of project proceedings > - Collaborate with clients, external CROs and suppliers > > *PROFILE & COMPETENCIES* > > The ideal candidate has a strong background in biochemistry, biophysics > or structural biology and at least 4 years of hands-on experience in > protein crystallization and structure determination using standard > crystallization software (e.g., CCP4, Phenix). Hands-on experience with > crystallization robots and understanding of molecular interactions in the > context of ligand modelling is desirable; a willingness to learn is > required. The multitude of ongoing projects in a rapidly changing > environment demands a flexible, creative, and highly organized person with > hands-on mentality and excellent communication skills. > > Required competencies include: > > - Problem analysis: ability to identify problems, recognize important > information, make connections between data, and trace possible causes of > problems > - Creativity: ability to come up with original solutions, and think > ‘out-of-the-box’ to design novel strategies > - Work standards: setting high quality standards with respect to > performance of experiments and data analysis, and act accordingly > - Oral and written communication: ability to communicate in a clear, > persuasive, and effective way to colleagues and clients about ideas, and to > report project progress in an accurate and reproducible manner > - Adaptability: ability to adjust one’s behavior, planning, and > organization in response to frequent changes, delays, and unexpected events > - Teamwork: ability to contribute actively to a joint result or > solution, even when such teamwork concerns a matter which is not of > immediate personal interest > - Tenacity: ability to stay with a plan of action or point of view > until the desired goal has been attained or is no longer reasonably > attainable > - Planning and organization: ability to plan and organize tasks and > projects to meet the defined goals > > Please send your CV, motivation letter and names of potential referees to < > h...@zobio.com*>* with the subject: “Scientist in Protein Crystallography”. > ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/