Postdoctoral positions - structural mechanisms of genome maintenance
Vanderbilt University

Description
Multiple NIH-funded postdoctoral positions are available in the laboratory of 
Dr. Brandt Eichman at Vanderbilt University to study molecular mechanisms of 
enzymes involved in DNA replication-repair. Projects include (1) repair and 
tolerance of DNA damage during replication, (2) resolution of stalled 
replication forks, (3) replication initiation, and (4) base excision repair of 
interstrand DNA crosslinks. We integrate the tools of structural biology, 
including cryo-EM, X-ray crystallography, and computational modeling, with in 
vitro biochemistry, biophysics, chemical and cell biology, and genetics to 
investigate the structure-function relationship of DNA processing enzymes and 
their macromolecular complexes.

The environment
Lab members are part of a collaborative, multidisciplinary, and inclusive team 
of investigators and trainees interested in DNA replication and repair. Fellows 
are trained in multiple disciplines and take advantage of state-of-the-art 
shared research facilities, including new cryo-EM and X-ray crystallography 
instrumentation. Scientific growth and professional development opportunities 
beyond the PI's laboratory are provided by the Genome Maintenance program 
within the Vanderbilt-Ingram Cancer Center, the Molecular Biophysics training 
program within the Center for Structural Biology, and other NIH-supported 
training grants. The PI's laboratory is committed to fostering a diverse and 
inclusive environment and welcomes applications from marginalized groups.

Vanderbilt University is located in the heart of Nashville, Tennessee, which is 
consistently rated as one of the best cities in the US in which to live and 
work.

Stipend
Salaries follow the NIH NRSA stipend scale. Additional information on benefits 
and being a postdoc at Vanderbilt University can be found at 
https://www.vanderbilt.edu/postdoc/.

Applicants
A Ph.D. in biochemistry, molecular biology, or a related discipline, and at 
least one first-author publication are required. Experience in cryo-EM, nucleic 
acid manipulation, and/or single-molecule techniques are highly desirable. The 
successful candidate will have a demonstrated productivity in protein 
biochemistry; have excellent organizational, interpersonal, and communication 
skills; and be willing take research risks and motivated to learn new 
techniques.

To apply
Email CV, a cover letter detailing your research interests and career goals, 
reprints of recent publications, and names of 3 references to 
brandt.eich...@vanderbilt.edu<mailto:brandt.eich...@vanderbilt.edu>.

Contact
Brandt Eichman, Ph.D.
brandt.eich...@vanderbilt.edu<mailto:brandt.eich...@vanderbilt.edu>
Phone: 615-936-5233
http://structbio.vanderbilt.edu/eichman/



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