POSTDOCTORAL POSITIONS

at Brown University, USA

 

The Deaconescu Lab at Brown University has two openings for postdoctoral 
researchers. The laboratory's interest is the interplay between DNA repair, 
transcription and other cellular processes ensuring microbial adaptation to 
stressful environments. We deploy a combination of biochemical, biophysical and 
structural techniques. (e.g. X-ray crystallography, small-angle X-ray 
scattering, transmission electron microscopy). For examples of work, please see 
Brugger et al, Nature Communications (2021), Dorich et al., Genes and 
Development (2019), Le et al. Cell (2018), Vemu et al., Science (2018), Kutter 
et al. JMB (2016), Szyk et al, Cell (2014). Positions are partially or 
completely funded from NIH grants.

 

         The first position is focused on protein purification, 
characterization and structure determination by X-ray crystallography. Previous 
experience with biophysical methods (ITC, MST, fluorescence) and enzymatic 
assays a plus.

 

         The second position will be focused on cryo-EM.  A successful 
candidate should be familiar with specimen preparation, data collection as well 
as the processing of images acquired using electron cryo-microscopy. We have 
our own Vitrobot for specimen vitrification and access to state-of-the art 
electron microscopes at Stanford/SLAC (remote data collection is possible) as 
well as a computing cluster. If needed further training in EM can be provided.

 

The candidates should also have the following qualifications: a Ph.D. in the 
field of structural biology or related field; an established track-record of 
publications in peer-reviewed journals.  Must be highly motivated and work 
independently as well as in a team. Excellent spoken and written English are 
required. New Ph.D. graduates are encouraged to apply.  The lab has its own 
Vitrobot, multiple protein purification platforms and a crystallization robot 
etc. Access to EM facilities also available.

 

         Interested candidates should send a CV, one page research experience 
summary and contact information for three references to 
alexandra_deacone...@brown.edu <mailto:alexandra_deacone...@brown.edu>. Salary 
and starting date are negotiable.   Please write Postdoctoral Candidate in the 
e-mail subject header.   Brown University, an Ivy League school, is located 
less than one hour away by train from Boston.   Lab webpage: 
https://deaconesculab.com


-- 
Alexandra Deaconescu, B.E., Ph.D.
Assistant Professor
Brown University

Office: (401) 863-3215
Wet Lab: (401) 863-6729
Computational Lab: (401) 863-7031

For Mail:
Laboratories of Molecular Medicine
70 Ship St. GE-4
Providence, RI 02903

For Courier:
Laboratories of Molecular Medicine
Brown University
70 Ship St., Chestnut St. Loading Dock
Providence, RI 02903

Website: www.deaconesculab.com

Admin
Ms. Tammy Glass
Email: tammy_glass[at]brown.edu
Mailing Address:
Box G-E, Brown University,
Providence, RI 02912-G
Telephone:     401-863-7446

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