Great paper indeed! However quite significant progress seems to have been achieved with ligands as well (and not only)… https://deepmind.google/discover/blog/a-glimpse-of-the-next-generation-of-alphafold/ Has anyone in the community put this to the test?
Best wishes Roberto Roberto A Steiner www.steinerlab.org<http://www.steinerlab.org/> https://twitter.com/steiner_lab roberto.stei...@kcl.ac.uk<mailto:roberto.stei...@kcl.ac.uk> Randall Centre for Cell and Molecular Biophysics Faculty of Life Sciences and Medicine King's College London Room 3.10A New Hunt's House, Guy's Campus SE1 1UL, London, UK Phone 0044 20 78488216 Fax 0044 20 78486435 roberto.stei...@unipd.it<mailto:roberto.stei...@unipd.it> Dipartimento di Scienze Biomediche Università degli Studi di Padova Viale G. Colombo 3 35131 Padova, Italia Telefono 0039 049 8276409 Responses to emails are not expected outside of your normal working hours. On 30 Nov 2023, at 22:35, Tom Terwilliger <0000b6116340b489-dmarc-requ...@jiscmail.ac.uk<mailto:0000b6116340b489-dmarc-requ...@jiscmail.ac.uk>> wrote: You don't often get email from 0000b6116340b489-dmarc-requ...@jiscmail.ac.uk<mailto:0000b6116340b489-dmarc-requ...@jiscmail.ac.uk>. Learn why this is important<https://aka.ms/LearnAboutSenderIdentification> Hi Structural biologist colleagues! Our article that helps you make the case that the experiment is still very much needed is now out: https://www.nature.com/articles/s41592-023-02087-4 "AlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structure determination." Nature Methods (2023) Also, here is a video on the Phenix Tutorials YouTube channel that describes this analysis: https://www.youtube.com/watch?v=ugMPYdPo8Bc (I hope you will be happy to see that you and your structural biology colleagues get the credit for making AlphaFold possible at 2:35 in the introduction of this video! Keep up the fantastic structural biology work!) All the best, Tom T -- Thomas C Terwilliger Laboratory Fellow, Los Alamos National Laboratory Senior Scientist, New Mexico Consortium 100 Entrada Dr, Los Alamos, NM 87544 Email: tterwilli...@newmexicoconsortium.org<mailto:tterwilli...@newmexicoconsortium.org> Tel: 505-431-0010 ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
