Hi Andre, I don't know if anyone mentioned Conservation-Colab, although it maps the conservation onto an AF model. https://zenodo.org/records/10062829
Cheers, Nick Nicholas Schnicker, PhD Director, Protein & Crystallography Facility Adjunct Assistant Professor, Molecular Physiology & Biophysics University of Iowa 51 Newton Rd, 4-611 BSB Iowa City, IA 52242 319-335-7671 ________________________________ From: CCP4 bulletin board <CCP4BB@JISCMAIL.AC.UK> on behalf of Andrew Gnann <adgn...@gmail.com> Sent: Thursday, January 4, 2024 8:29 AM To: CCP4BB@JISCMAIL.AC.UK <CCP4BB@JISCMAIL.AC.UK> Subject: [External] Re: [ccp4bb] alternatives to Consurf server Hi Andre, I recently prepared a Consurf-like figure using conservation scores pulled from alignments in JalView. You would follow instructions for running data2bfactor.py in PyMOL, feeding the conservation scores to replace your model's B factor column. Then set up a color ramp like you would use to display B factors. Please let me know if you go this route and run into issues. Here is a link to a copy of data2bfactor.py: https://gist.github.com/Croydon-Brixton/ca916769c285faed69740d384b5daf23 Best, Andrew On Thu, Jan 4, 2024, 9:07 AM Andre Godoy <00000b9d7671a1b6-dmarc-requ...@jiscmail.ac.uk<mailto:00000b9d7671a1b6-dmarc-requ...@jiscmail.ac.uk>> wrote: Dear CCP4ers, Wishing you all a Happy New Year! You may have noticed that the Consurf server has been down since the conflicts in the Middle East began. Does anyone know of alternative tools that can provide similar results? Best regards. Andre S. Godoy, PhD Universidade de São Paulo Instituto de Física de São Carlos Av. João Dagnone, 1100, Jd. Santa Angelina 13563-120 - São Carlos, SP, Brazil ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 ________________________________ To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/