Northwestern University seeks to recruit an enthusiastic and motivated 
cryo-electron microscopy (cryo-EM) Facility Manager to join the Structural 
Biology Facility (SBF), located on the Evanston campus. The successful 
applicant will be responsible for managing a new Krios instrument and 
contributing to basic and translational research programs on both the Evanston 
and Chicago campuses. The SBF cryo-EM facility currently houses a TFS Glacios 
and JEOL 1400 TEM. In addition, a new TFS Krios G4 will be operational in 
September of 2025. The Krios is equipped with a Selectris energy filter and a 
Falcon 4i direct electron detector. Several instruments for sample preparation 
are also available as part of the SBF.

Primary Responsibilities: 

Train and assist users in cryo-EM sample preparation, screening, and data 
collection
Provide guidance to users on sample preparation, data collection, and the use 
of current image processing programs
Help with administration of the Krios related portion of SBF (scheduling, 
billing, report writing, grant writing)
Promote the Krios, and SBF in general, and participate in hands-on, group 
teaching of EM methods
Contribute to the development and implementation of new EM experimental methods 
and protocols
Maintain instruments to ensure optimal performance and high-quality sample 
preparation and data acquisition at all times
Prepare samples and collect EM data for users who request staff service
Minimum qualifications:

Masters or Ph.D. degree with three years of hands-on cryo-EM experience in an 
EM laboratory.
Preferred qualifications:

Ph.D. degree in biochemistry, biology, chemistry, physics or related field
Experience in the use of TFS and JEOL microscopes and sample preparation
Experience with cryo-EM data collection software (SerialEM and/or EPU) and 
image processing software packages (Relion, CryoSPARC, etc.)
Prior experience with different aspects of structural biology research, such as 
data collection, structure determination, model building, and refinement
Excellent technical, teaching, and verbal and written communication skills
Ability to work with others and as a team member
This position will report to the Facility Director. Salary commensurate with 
qualifications and experience. Northwestern University provides excellent and 
competitive benefits.

Please submit your CV and ask for 2-3 reference letters to be directly sent to 
[email protected]. For full consideration, please submit your 
application by May 29, 2026.

Northwestern University is an Equal Opportunity, Affirmative Action Employer of 
all protected classes. Women, racial and ethnic minorities, individuals with 
disabilities, and veterans are encouraged to apply. Hiring is contingent upon 
eligibility to work in the United States.

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