ok I went and looked anyway. It does say that there is a benefit if the
doses are pooled. Not quite sure what that means, but it does tend to
indicate that the issue is a little more complex than you portray it to be.
Again.

Dana


On 12/4/05, Dana <[EMAIL PROTECTED]> wrote:
>
> tsk as usually you are poo pooing without reading. You'd be funny if you
> weren't so condescending. The attitude of real science indeed.
>
> Hello, I am talking about anticoagulation, as Sam has already realized.
> Remember that the next time you call him a Neanderthal.
>
> As for your study, don't have time. It may say this but given your track
> record I am willing to bet it says more than that too. In any event there
> are other studies, peer-reviewed, my friend. See the archives; posted them
> this summer. Ther aren't a lot -- there are problems with establishing a
> standard does as I have already mentioned.
>
> Dana
>
>
>
> On 12/4/05, Larry C. Lyons <[EMAIL PROTECTED]> wrote:
> >
> > I think that this Cocheran based meta analysis summarizes the attitude
> > of real science, there is no real effect for ginko beyond a placebo.
> >
> > http://www.antiwrap.com/?789
> >
> > Ginkgo biloba Compared with Cholinesterase Inhibitors in the Treatment
> > of Dementia: A Review Based on Meta-Analyses by the Cochrane
> > Collaboration
> > A. Kurza, B. Van Baelenb
> >
> > aDepartment of Psychiatry and Psychotherapy, Technical University
> > Munich, Munich, Germany;
> > bMedisearch International, Mechelen, Belgium
> >
> > Dementia and Geriatric Cognitive Disorders 2004;18:217-226 (DOI:
> > 10.1159/000079388)
> >
> > Abstract
> >
> > Data were derived from the Cochrane Collaboration meta-analyses of the
> > efficacies of ginkgo, donepezil, rivastigmine and galantamine on
> > changes in cognitive function in patients with dementia and, where
> > necessary, were transformed to standardized mean differences. The
> > proportion of patients discontinuing trials was used as a proxy
> > measure of tolerability. Outcomes were assessed after 6 months of
> > treatment. Trial data for cholinesterase inhibitors were more
> > consistent than those for ginkgo, particularly regarding patient
> > populations and outcome measures. Significant benefits on cognition
> > vs. placebo were seen with donepezil, 5 and 10 mg, rivastigmine, 6-12
> > mg, and galantamine, 16 and 24 mg. Significant benefit vs. placebo
> > with ginkgo was seen only when all doses were pooled. Similar
> > proportions of patients discontinued treatment with ginkgo and
> > placebo. Cholinesterase inhibitors were also well tolerated, although
> > a significantly greater proportion of patients receiving active
> > treatment discontinued vs. placebo with some doses. An evidence-based
> > medicine approach, taking into account the quality of clinical trials,
> > is essential when assessing the safety and efficacy of medications.
> > --
> >
> > 

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