> ***No. However, I'd be very interested in specific research that shows
> that careful selection of  dogs that don't have hip, eye, heart and
> patella defects coupled with attempts to reduce in-breeding leads to
> immune disorders or the early onset of cancer.

Will Fanconi's Syndrome suffice???

http://www.jabed.com/genes.htm

Long story made short, as Basenji breeders were trying to eliminate pyruvate
kinase hemolytic anemia which is fatal they wound up increasing progrsseive
retinal atrophy and Fanconi's syndrome which is also fatal. Fortunately breeders
through the parent club were able to pursuade AKC to re-open the stud book and
allow native stock from Africa to be imported.
http://www.basenji.org/african/brow8907.htm

Terrie

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