For those wondering like me what "Direct Linking" is, here are a few links 
I could find. This seems to be a very old possible improvement to Clojure 
which is being looked at again.

http://dev.clojure.org/display/design/Build+Profiles
https://groups.google.com/forum/#!msg/clojure-dev/guT3QBEg5w0/9deJ5E0AW9sJ
https://groups.google.com/forum/#!msg/clojure-dev/guT3QBEg5w0/e6m0RZ0yk4gJ

On Thursday, July 30, 2015 at 10:51:18 AM UTC+12, Alex Miller wrote:
>
> Clojure 1.8.0-alpha3 is now available.
>
> Try it via
> - Download: 
> https://repo1.maven.org/maven2/org/clojure/clojure/1.8.0-alpha3
> - Leiningen: [org.clojure/clojure "1.8.0-alpha3"]
>
> Tuples have been disabled after further analysis of performance impacts.
>
> This alpha has initial support for direct linking which you can enable 
> with -Dclojure.compiler.direct-linking=true
>
> Direct linking allows functions compiled with direct linking on to make 
> direct static method calls to most other functions, instead of going 
> through the var and the Fn object. This can enable further optimization by 
> the jit, at a cost in dynamism. In particular, directly-linked calls will 
> not see redefinitions.
>
> In alpha3, clojure.core is compiled with direct linking by default and 
> therefore other namespaces cannot redefine core fns and have those 
> redefinitions seen by core code.
>
> Functions declared as dynamic will never be linked to directly.
>
> As with all alphas, this represents ongoing work-in-progress that is 
> subject to change.
>

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