I used to be very thick skinned,cuts and scrapes healed 
quickly,bleeding stopped in seconds usually.It was a good thing, 
because I was a carpenter and always getting cuts slivers and 
bruises.  Then I got cml and my skin became so thin and easily 
damaged I could no longer effectively do carpentry. Any little cut on 
the hands would mean I would have to stop working untill it healed or 
there would be blood all over my project. I also get skin rashes. I 
originally thought it might be caused by Intrferon, but when I 
switched to Gleevec  it didn't improve. It is probably something I 
will just have to live with,as doctors don't seem too concerned about 
it. I try not to do anything that is hard on the hands, or at least 
wear gloves more often.This has been my experience,perhaps others can 
suggest something more helpful.----------
                                Richard S-----------------------------
--- In [EMAIL PROTECTED], [EMAIL PROTECTED] wrote:
> My son has blessedly few serious side effects on Gleevec.  His skin 
seems to 
> be the thing most affected by it.  He has experienced 
hypopigmentation for 
> four years or so.  Then, more recently, his skin seems more fragile 
and 
> susceptible to cuts and scrapes.  He has complained of bruising as 
well.  Has anyone 
> else experienced this side effect, and can anything be done about 
it?  
> Thanks...Rosemary C.



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