Alexis, I hope your dad is feeling better soon. Fatigue is also very common, especially if his blood counts are off. The medicine will also cause weakness and fatigue, but most time the side effect from the medicine decrease with time. As much as he can he needs to do a little exercising each day, it helps with his energy level. I know on the days I veg out and do nothing I have less energy. The days I get up and move around I feel better. Since he's on 800mg he could break it up and take 400mg in the morning and 400mg in the afternoon, that might help with the nausea and weakness. If his WBC is going back up it could mean he's no longer responding to the medicine but I would imagine his onc should be doing more tests to confirm that. If you feel he is continuing to get worse you might suggest he find the closest cancer center and get a second opinion. They will have the most up to date information to help him. Take Care! Brenda
--- In [email protected], "alcotta" <[EMAIL PROTECTED]> wrote: > > Brenda, > Thanks for your relpy. My dad was on 400mg Gleevec and they doubled > his dose to 800mg. He has much more side effects now. He doesn't > like to talk about any of his health issues (very private stubborn > guy), but I notice he is much weaker and has much more nausea. > Thanks for the info on the side effects. It helps to know what > others are experiencing. He lives in a small town so I am not > confident in his oncologist keeping up on the latest information. > > At one point his testing showed no more Phillidelphia chromosome, yet > his WBC count went up again after this so I don't know what this > means. > > I've been reading a lot on the site and it really helps to learn more > about what is going on. > > Hope you all had a wonderful Christmas. > Alexis > > --- In [email protected], "Brenda Morelli" <[EMAIL PROTECTED]> wrote: > > > > Welcome Alexis, > > What dose of Gleevec was he on? It could be he just needed a > higher > > dose. Had you reached any level of remission? There are Gleevec > > treatments where they are combining with other meds now. There's > > also various trials going on for new treatments. What did your onc > > say about the situation? Englarged spleen could be causing your > dad > > pain, this is typical in leukemia. Side effects vary from each > > person, the most common are: joint & muscle pain/cramps, diarrhia, > > Edema around the eyes, nausea & headaches. This is a great sight > to > > get information. I hope your dad improves soon. Take care. > > Brenda > > dx 5/04 > > Gleeve 6/04 > > 6mth bmb, pending results > > > > > > --- In [email protected], "hey00nanc" <[EMAIL PROTECTED]> wrote: > > > > > > --- In [email protected], "alcotta" <[EMAIL PROTECTED]> wrote: > > > > > > > > > > > After his first 1 1/2 years on Gleevec, his white blood count > > > started > > > > to raise again so they doubled his dose and that worked. Does > > this > > > > mean that some people will build up a tollerance to the > > medicine? I > > > > know that Gleevec has only been on the market for a few years > but > > > > does anyone know about studies on how long it works? I've been > > > > reading about "super Gleevec" and the Bristol Myers BMS- > 354825. > > > > Sounds very promising. > > > > > > > > Also I'm curious about the side effects from Gleevec. My dad > is > > > > often grasping his side like he has some type of pain - is that > > > > common? Are there any other common side effects? > > > __________________ > > > > > > Hi Alexis, > > > > > > You can develop a mutation that makes your leukemia cells less > > > sensitive to Gleevec.....and then a higher dose is sometimes an > > > effective treatement change. > > > > > > If you just joined the list, I would encourage you to go back to > > the > > > beginning of December (you can read old posts from the website) > and > > > look for the posts from Cheryl-Anne and Mark with reports from > the > > > annual ASH (Amer. Society of Hematologists) conference. There are > > some > > > good summaries about all this information...all the latest > > findings. > > > > > > Also, you can find a lot of information, about side effects and > > > remedies, etc. on this website of one of our listmembers: > > > www.cmlsupport.com > > > this is a good starting place to get lots of info about cml and > > > Gleevec treatment. > > > > > > Hope this info helps. > > > Nancy C. ------------------------ Yahoo! Groups Sponsor --------------------~--> $4.98 domain names from Yahoo!. Register anything. http://us.click.yahoo.com/Q7_YsB/neXJAA/yQLSAA/8zSolB/TM --------------------------------------------------------------------~-> New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: [email protected] Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/CML/ <*> To unsubscribe from this group, send an email to: [EMAIL PROTECTED] <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
