Based on surprising results from animal experiments, researchers at The University of Texas M. D. Anderson Cancer Center have revamped common beliefs about how chronic myeloid leukemia (CML) functions within bone marrow - a discovery they hope may some day lead to additional therapeutic strategies.

In a study presented at the annual meeting of the American Association for Cancer Research (AACR), they found that CML does not "crowd out" normal blood cells in the bone marrow, as has long been thought, but actually kills those healthy cells through use of a unique cell "death factor."



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