With all the positive things that have been making the news about CML and Gleevec on CNN, Reader's Digest and other articles it is ashame that ER only spotlighted the subject with wrong info. Once again Barb thanks for confirming what I had heard last night.
Suzan
Barb Neddo <[EMAIL PROTECTED]> wrote:
Barb Neddo <[EMAIL PROTECTED]> wrote:
This is what I found at
http://www.cancerbacup.org.uk/Cancertype/Leukaemiachronicmyeloid/
Causesdiagnosis/Diagnosis
Philadelphia chromosome
Most people with CML have a genetic abnormality known as a Philadelphia
chromosome which can be detected by laboratory tests. Every cell in the
body has a nucleus that contains chromosomes. Chromosomes are long
structures made up of DNA. DNA determines how the cell looks and acts.
The Philadelphia chromosome develops when part of chromosome 9 (the ABL
gene) wrongly attaches to chromosome 22 (the BCR gene) during cell
division. This creates a new gene, known as BCR-ABL which produces a
specific new protein. The protein causes the production of an enzyme
called tyrosine kinase, which leads to the chronic phase of CML by
stimulating the production of abnormal blood cells by the bone marrow.
The Philadelphia chromosome is not inherited and cannot be passed on to
your children.
The email for ER is [EMAIL PROTECTED]
Barb
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