Are there any studies that show the effects of reducing the Gleevec
dose after achieving PCRU?  I've seen a fair amount of anecdotal
information, but nothing scientific.

I achieved 3 log on 400/day.  Went to 600 and almost immediately became
PCRU where I've remained going on 9 months.  I'd like to reduce the
dose to mitigate side effects, but my Dr. thinks we ought not to screw
around with something that is working.  SInce he specializes in CML, I
suspect he'd know if such a study existed, but thought I'd ask anyway.

Mike Burwen


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