Generally, as you have noted, you have slightly high WBCs, which are mainly due to a high neutrophil count (neutrophilia). Since you have increased Gleevec dosage to 600mg somewhat recently as I recall, you could expect some CBC issues, but normally you would expect the WBC to drop, not increase. You show signs of anemia (low HGB and HCT), even though RBC is normal. The high neutrophil count could be caused by an infection, injury, kidney problems or other issues, so you should not rule those out. If you cannot recall recent infections or injury, I would encourage you to ask the docs to figure this out by doing some testing. Your WBC is just slightly high, but it can also be a sign of Gleevec resistence when WBC steadily rises, especially after increasing the Gleevec dosage, and coupled with your recent platelet issues it deserves attention. I could not find your latest PCR, FISH and BMB info here -- what is your recent history for these tests? You might want to discuss with your Onc having a PCR and also a BCR-ABL Mutation Test (aka, Gleevec Resistence Test). Here is one lab's description of the latter test (there are also other labs that do it): http://www.aruplab.com/guides/ug/tests/0040138.jsp
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