Many CMLers have yo-yo-ing results: undetectable for months and then suddenly a little rise and then the next time it will be undetectable again and so on. My onc watches the trend rather than over-reacting at the first change. If it yo-yos within narrow parameters, she doesn't get excited but just watches it over time. If it suddenly starts showing an important rise, then she'll do something about it.
On Sun, May 29, 2011 at 6:23 AM, <cmlhope+nore...@googlegroups.com> wrote: > Today's Topic Summary > > Group: http://groups.google.com/group/cmlhope/topics > > - Question re; BCR-ABL > results<https://mail.google.com/mail/html/compose/static_files/blank_quirks.html#1303b47e0d879f7f_group_thread_0>[2 > Updates] > - Question re; BCR-ABL > results<https://mail.google.com/mail/html/compose/static_files/blank_quirks.html#1303b47e0d879f7f_group_thread_1>[1 > Update] > > Topic: Question re; BCR-ABL > results<http://groups.google.com/group/cmlhope/t/3c0802ba2c0d20a8> > > cjb <cjbenne...@hotmail.com> May 26 05:20PM -0700 > ^<https://mail.google.com/mail/html/compose/static_files/blank_quirks.html#1303b47e0d879f7f_digest_top> > > My husband was diagnosed with CML in 2009. His BCR-ABL results were > undetectable at the 12 month markc with 400 mg of Gleevec. But, at > the 18 month mark his BCR-ABL result was again detectable (.005). He > will get retested again in July. Is this a typical experience for CML > patients (undetectable then detectable again)? Does it mean that he > is becoming resistant to the Gleevec? We would welcome insights from > those with more experience with CML. Thank you very much. > > > > > Ricardo Gadelha <ricardodgade...@gmail.com> May 28 04:23PM -0300 > ^<https://mail.google.com/mail/html/compose/static_files/blank_quirks.html#1303b47e0d879f7f_digest_top> > > This is not a big deal. My son was diagnosed in may 2007 and his PCR > have > never was undetectable , it goes up and down all the time. If it goes > up by > 100 times the last value, you should talk to your Doc - in your case by > PCR > > 0.5 > > > On Thu, May 26, 2011 at 9:20 PM, cjb <cjbenne...@hotmail.com> wrote: > > > -- > Ricardo > > > > Topic: Question re; BCR-ABL > results<http://groups.google.com/group/cmlhope/t/53658c682d0283a8> > > lblaine...@comcast.net May 28 06:31PM > ^<https://mail.google.com/mail/html/compose/static_files/blank_quirks.html#1303b47e0d879f7f_digest_top> > > I was on Gleevec for 1 1/2 years then my numbers started going up. I > was then put on Sprycel 140mg which I was unable to tolerate, so they > lowered the dosage to 100mg and it put me back undetectable very quickly. > With Gleevec you have to be careful with Tylenol products, and acid reflex > medications. I don't remember if my Onc let me go another one or two months > after my numbers started going up. I'm pretty sure he switched me almost > immediately to Sprycel. > > Lenda Coleman > ----- Original Message ----- > From: "cjb" <cjbenne...@hotmail.com> > To: "CMLHope" <cmlhope@googlegroups.com> > Sent: Thursday, May 26, 2011 7:20:12 PM > Subject: [CMLHope] Question re; BCR-ABL results > > My husband was diagnosed with CML in 2009. His BCR-ABL results were > undetectable at the 12 month markc with 400 mg of Gleevec. But, at > the 18 month mark his BCR-ABL result was again detectable (.005). He > will get retested again in July. Is this a typical experience for CML > patients (undetectable then detectable again)? Does it mean that he > is becoming resistant to the Gleevec? We would welcome insights from > those with more experience with CML. Thank you very much. > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google > Groups "CMLHope" group. > To post to this group, send email to CMLHope@googlegroups.com > To unsubscribe from this group, send email to > cmlhope-unsubscr...@googlegroups.com > For more options, visit this group at > http://groups.google.com/group/CMLHope > > > > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to CMLHope@googlegroups.com > To unsubscribe from this group, send email to > cmlhope-unsubscr...@googlegroups.com > For more options, visit this group at > http://groups.google.com/group/CMLHope -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to cmlhope-unsubscr...@googlegroups.com For more options, visit this group at http://groups.google.com/group/CMLHope
