URL REFERENCE:
https://matthieugilson.eu/positions/Post-Doc_neuroimaging_biomarkers.html
JOB TITLE
Post-doctorate position to study diagnosis of multimodal neuroimaging data for
amyotrophic lateral sclerosis
RESEARCH FIELDS
Data Science, Neuroimaging, Neurology, Computational Neuroscience
PROJECT DESCRIPTION
The project aims to develop and test prediction tools for clinical diagnosis
from neuroimaging data, with pipelines covering data preprocessing and
machine-learning representational techniques. The focus is on amyotrophic
lateral sclerosis (ALS), a rare neurodegenerative disease for which no
efficient treatment exists. A particular goal is to test the possibility of
stratifying ALS patients in subtypes with slow versus fast disease progression.
It is based on a dataset of 30 ALS patients and matched controls, acquired on
7T and 3T magnetic resonance imaging (MRI) scanners, which is currently being
extended. Specifically, this dataset involves advanced MRI techniques that are
promising for neurodegenerative diseases: quantitative and sodium MRI
modalities, in addition to usual structural and functional MRI. We thus plan to
build a multimodal prediction pipeline such as to test the combination of
distinct types of MRI data (graph/network fusion) for clinical prediction. It
also includes an international collaboration and aims to compare ALS datasets
acquired in different centers.
The position lies at the intersection between clinical research in a hospital
and a neuroscience laboratory, aiming to bridge the different research cultures
from both sides. We provide an interdisciplinary environment with a team of
experts in the following fields:
• computational neuroscience with Matthieu Gilson
(https://matthieugilson.eu) and Xenia Kobeleva (https://xenia-kobeleva.com/),
• MRI techniques with Wafaa Zaaraoui
(https://crmbm.univ-amu.fr/contact/zaaraoui-wafaa),
• neurology with Aude-Marie Grapperon
(https://loop.frontiersin.org/people/593696) and again Xenia Kobeleva.
JOB OFFER
The position consists of 2 contracts for a total duration of 18 months (full
time, 35 hours / week), because of combining two sources of funding. The
monthly net salary is between 2000 to 2500 euros depending on previous working
experience. The work place is at the Institut de Neurosciences de la Timone
(INT, https://int.univ-amu.fr) and Center for Magnetic Resonance in Biology and
Medicine (CRMBM, https://crmbm.univ-amu.fr), both part of Aix-Marseille
University (France).
Start date: October 2023
REQUIRED QUALIFICATIONS AND PROFESSIONAL SKILLS
We are looking for a candidate that can demonstrate sufficient experience at
the PhD level and knowledge in data analysis for neuroscientific data for
reaching the project objectives. We seek profiles with solid programming skills
in Python (or an equivalent language) combined with a background in the field
of neurology. Experience in clinical neuroimaging, markers for neuropathologies
and/or computational neuroscience will be favored. Additionally, experience
with working in a interdisciplinary team and interest for open science are
desired. Women are strongly encouraged to apply. The candidates will also be
evaluated on their motivation, with respect to all steps of the process from
data acquisition to analysis and scientific communication.
CONTACT AND REQUESTED DOCUMENTS
Please send a curriculum vitae summarizing your academic and professional
trajectory, as well as a motivation letter, to: [email protected]
--
Matthieu Gilson
Chaire de Professeur Junior
Aix-Marseille Université
Institut de Neurosciences de la Timone
https://matthieugilson.eu
