Seems to stomp memory.  A work around is to declare the parameter as a 
POINTER(GUID) instead of GUID and pass a copy of the GUID instance byref 
[this should be what happens under the covers].  I'm not sure if this is a 
comtypes or ctypes issue; it likely applies to other "large" datatypes as 
well.  I'm using python-2.5.2.amd64.msi, 
ctypes-1.0.2.win32-py2.5-AMD64.msi and comtypes-0.4.2.zip. 

Peter
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