On 30/01/2017 23:02, Jan Abendroth wrote:
I am refining a protein with 16 copies of the same chain per ASU. Fortunately,
it is a small
protein.
Coot has become really slow for this structure. Any real space refinement or
placement of a
water makes coot for 10+ seconds unresponsive. The coot backup files aren't
that large,
around 700k.
Not displaying NCS and using a small radius for crystallographic symmetry does
not help.
I am using a MacBook Pro 2.6GHz i5, 8GB RAM, Intel IRIS 1534 MB, flash hard
drive. I has
never been that slow for 50+ structures.
I've not seen such behaviour.
Possible reasons
1) NFS (slow backups)
2) NCS (matrix updates)
3) symmetry calculation
Paul.
