-Caveat Lector-

http://www.lasvegassun.com/sunbin/stories/thrive/2003/apr/02/040206755.
html
April 02, 2003

Study: Flu Shots Prevent Heart Disease

By STEPHANIE NANO
ASSOCIATED PRESS

Flu shots may do more for the elderly than fend off the flu bug - they also
protect against heart disease and stroke, new research shows.

Results of a large study of more than 286,000 elderly, appearing in
Thursday's New England Journal of Medicine, show hospital stays for heart
disease or stroke during two flu seasons were substantially reduced among
those who got flu shots.

"Influenza may be even worse than we thought. And flu shots might be
even better than we thought," said researcher Dr. Kristin Nichol of the
Minneapolis Veterans Affairs Medical Center.

New government figures show influenza contributes to an average 36,000
annual U.S. deaths.

Flu shots are now recommended for all adults 50 and older. In 2001, about
63 percent of those over 65 were vaccinated in the United States.

The flu vaccine reduces deaths overall and prevents pneumonia in the
elderly, and some small studies have suggested that they help ward off
heart disease and strokes.

The researchers checked medical records for those over 65 enrolled in
three managed-care plans in the Minneapolis, Portland, Ore., and New
York City areas during two flu seasons - 1998-1999 and 1999-2000. Of the
140,055 people studied in the first flu season, 56 percent were vaccinated.
In the second, 60 percent of the 146,328 enrollees got flu shots.

They compared hospital stays for those who got shots and those who
didn't. Flu vaccination cut hospitalizations for heart disease by 19 percent
both seasons, the findings showed. Hospital stays for stroke were reduced
by 16 percent the first season and 23 percent the second.

"There are very few things we can do in medicine that provide these kinds
of benefits over a very short period of time. This is huge," said Nichol.

Dr. William Schaffner, head of preventive medicine at Vanderbilt University
School of Medicine, said the results need to be investigated further but
reinforce an important message.

"It offers even more reassurance and affirmation as to the importance of
getting your flu shot annually," said Schaffner.

The researchers also found immunization cut hospital stays by about one-
third for the flu and pneumonia, a common complication, and reduced by
half the risk of death from any cause. The findings are similar to previous
studies.

Nichol said the connection between the flu and heart disease and stroke
isn't clear but the virus could be affecting blood vessels and the
development of clots in the brain and heart.

Schaffner said there should be a national program to provide flu shots,
noting that the government has launched a smallpox vaccine program
without a single case.

"We have an estimated 20-30,000 deaths due to influenza. We need an
organized, national vaccine program each year," he said.

---

On the Net:

New England Journal: http://www.nejm.org

CDC flu information: http://www.cdc.gov/ncidod/diseases/ flu/fluvirus.htm

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