-Caveat Lector-
Science 13 July 2007: Vol. 317. no. 5835, pp. 215 - 219 DOI:
10.1126/science.1139560 Research Articles - Prefrontal Regions Orchestrate
Suppression of
Emotional Memories via a Two-Phase Process - Brendan E. Depue, Tim Curran,
Marie T. Banich Whether memories can be suppressed has been a controversial
issue
in psychology and cognitive neuroscience for decades. We found evidence that
emotional memories are suppressed via two time-differentiated neural
mechanisms: (i) an initial suppression by the right inferior frontal gyrus
over
regions supporting sensory components of the memory representation (visual
cortex, thalamus), followed by (ii) right medial frontal gyrus control over
regions
supporting multimodal and emotional components of the memory representation
(hippocampus, amygdala), both of which are influenced by fronto-polar
regions. These results indicate that memory suppression does occur and, at
least in
nonpsychiatric populations, is under the control of prefrontal
regions.....E-mail: depue{at}colorado.edu
_http://www.sciencemag.org/cgi/content/abstract/317/5835/215_
(http://www.sciencemag.org/cgi/content/abstract/317/5835/215)
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