September 8 2000  BRITAIN

Strangelove syndrome gives hands a life of their own

A MAN who tried to strangle himself in the middle of the night has
been found to be suffering from "Dr Strangelove syndrome". The
previously unrecognised conditon, which has been diagnosed in 40
people in Britain and around the world, leaves people with an unruly
and uncontrollable hand that refuses to behave. Like the crazed doctor
played by Peter Sellers in the 1963 Stanley Kubrick film, the patients
have to use their other hand to control the wayward one.

The sufferers find that, despite their best intentions, the hand will
pick up objects such as scalding cups of coffee or steal ice creams
and other food from friends.

Sergio Della Sala, Professor of Neuropsychology at the University of
Aberdeen, said that many of the victims were at war with the
"anarchic" hand, using the one they could control to slap, grab and
scold it. He said one patient was so distressed that he kept his
unruly hand tied behind his back to avoid embarrassment.

Others, some of which he showed on video, plead with the hand, saying
"Please don't grab it, please don't grab" and "Little hand, behave".
Some have demonised the hand, believing it to be mad.

"One hand is behaving in a capricious way and performs an action the
patient does not want to perform while he or she tries to perform the
action they do want to perform with the other hand. So the two hands
end up fighting one another. It has been nicknamed Dr Strangelove
syndrome," Professor Della Sala said.

The victims, some of whom he has been studying, developed their
anarchic hand after a stroke or a car accident had damaged part of the
brain's frontal lobe known as the supplementary motor area. He said
that the research might shed light on a possible centre in the brain
controlling self-will.

Some researchers have suggested that people have two selves in which
one dominates the other.

Professor Della Sala said it might be that the brain damage passes
control from the normally dominant self to the less dominant one.

The condition might also affect other parts of the body. The professor
said that he was aware of at least one patient with an "anarchic"
foot.

He said that the syndrome probably affected far more people than the
40 already identified, but that it was being mistakenly treated as a
mental illness or one requiring physiotherapy.

He hopes that by publicising the condition victims may get more
sympathy, although he said that he was doubtful that a treatment or
cure could be found soon.

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