3 PEOPLE TEST POSITIVE FOR WEST NILE VIRUS
- -----------------------------------------------
2 Individuals Are Hospitalized In Stable Condition, and One Individual Has
Been Released From The Hospital

4 New Mosquito Pools Also Test Positive for West Nile Virus

New York City Health Commissioner Neal L. Cohen, M.D., announced today [12
Sep 2000] that 3 additional individuals have tested positive for West Nile
virus in New York City: a 77 year-old man from Florida who was staying in
Canarsie, Brooklyn, is hospitalized in stable, and improving condition; a
54 year-old man who is known to spend time in both Sunset Park, Brooklyn
and Cliffside Park, N.J. is hospitalized in stable, and improving,
condition; and a 40 year-old woman from Castleton Corners, Staten Island,
who has been released from the hospital and is recovering at home. The
laboratory results were obtained by tests performed at the New York City
Department of Health's laboratories, and specimens have been sent to the
U.S. Centers for Disease Control and Prevention (CDC) for further
confirmation. There is now a total of 11 people who have been diagnosed
with West Nile virus in New York City in 2000. Dr. Cohen made this
announcement at a news conference this evening with Mayor Rudolph W. Giuliani.

The Florida resident who was staying in Brooklyn became ill on 27 Aug 2000,
was admitted to the hospital with encephalitis on 3 Sep 2000, and remains
hospitalized in stable, and improving, condition. The man who has been
known to spend time in Sunset Park, Brooklyn and Cliffside Park, N.J.
became ill on 31 Aug 2000, and was admitted to the hospital with
encephalitis on 4 Sep 2000. He remains hospitalized in stable, but
improving, condition. The Staten Island woman became ill on 2 Sep 2000, was
admitted to the hospital on 5 Sep 2000 and was released from the hospital
on 11 Sep 2000.

"We will continue our extensive public outreach activities to inform the
public about our spraying activities for West Nile virus, including
scheduled radio announcements on WCBS radio, the City's West Nile
Information Line, the Health Department's website, print media, and other
media outlets. In addition, our spraying activities are escorted by New
York City Police Department vehicles with loudspeakers to help make
individuals in the vicinity of scheduled spraying operations aware of
spraying activities that will take place in that area," Dr. Cohen concluded.

MOSQUITO FINDINGS
The positive West Nile findings announced today include the 4 mosquito
pools on Staten Island: 3 from Grasmere (one pool was collected on 8 Aug
2000, one pool was collected on 25 Aug 2000, and one pool was collected on
26 Aug 2000), and one pool from Rossville (collected on 25 Aug 2000). All
of these areas were sprayed subsequent to these findings.

For information on West Nile virus, spraying activities, spraying
precautions, or to report dead birds and areas of standing water where
mosquitoes breed, New Yorkers can call the Health Department's West Nile
virus information line, 24 hours a day, 7 days a week, at 1-877-WNV-4NYC
(1-877-968-4692). From 9 Mar 2000 to 6 Sep 2000, the Health Department West
Nile virus Information Line has received approximately 90 000 telephone
inquiries. (New Yorkers who use TTY/TDD can call 212-788-4947 weekdays from
9:00a.m. to 5:00p.m.). Extensive information is also included on the City's
Web site at <nyc.gov/health>.

West Nile Virus Findings Summary Summary of West Nile Virus Findings as of
12 Sep 2000: 11 humans, 99 birds, and 109 mosquito pools

Borough Findings:

Staten Island:
Birds: 45
Mosquito Pools: 88
Humans: 8 (7 at home recovering, 1 hospitalized)

Manhattan:
Birds: 19
Mosquito Pools: 8

Queens:
Birds: 17
Mosquito Pools: 4

Bronx:
Birds: 8
Mosquito Pools: 4

Brooklyn:
Birds: 10
Mosquito Pools: 5
Humans: 2 (hospitalized)

Person spends time in Brooklyn and New Jersey:
Humans: 1 (hospitalized)

- --
ProMED-mail
<[EMAIL PROTECTED]>

[It is of interest that there have been no confirmed human fatalities
reported due to WNV in the United States thus far this year despite
intensive monitoring. -Man. Ed. DS]
........................................ds

-------------------------------------------------------------------


Date: Thu, 14 Sep 2000 20:46:43 -0400 (EDT)
From: ProMED-mail <[EMAIL PROTECTED]>
Subject: PRO/AH/EDR> West Nile virus, horses - France (02)

WEST NILE VIRUS, HORSES - FRANCE (02)
***************************************
A ProMED-mail post
<http://www.promedmail.org>

[see also:
West Nile virus, horses - France 20000912.1561]

Date: 14 Sep 2000 10:15:28
From: Herve Zeller <[EMAIL PROTECTED]>


West Nile virus was first isolated in Camargue, in the Rhone delta, south
of France, in Sep 1964 from _Culex modestus_ mosquitoes and 2 entomologists
on field work. It was then recovered from the same mosquito species in Jul
1965 and [from] a horse in Sep 1965 (Hannoun C et al, CR Acad Sc Paris,
1964, 259, 4170-4172).

Previous evidence of West Nile circulation was suspected during the summer
1962, in the same area when meningoencephalitis were [was] recorded in
horses. Among a group of 500 horses, 50 animals were sick (morbidity 10%)
with a fatality rate of 25-30%. Most of the cases were reported from
mid-Aug to mid-Sep 1962. Antibodies to West Nile were confirmed in
1963-1964 by Neutralization Test in 12 out of 47 horses. A retrospective
study on sick patients from the area during this summer 1962 showed
antibodies to Group B arboviruses in several individuals. Among these, a
young girl in Arles with febrile illness and meningitis showed a
seroconversion for Group B arboviruses (Joubert L et al, Ann Inst Pasteur,
1970, 118: 239-247).

Serological surveys in horses and humans during the period 1975-1980 did
not show evidence of recent circulation of the virus in this region (Rollin
PE et al, Med Mal Infect, 1982, 77-80)

Summer 2000

2 serum specimens from horses for WN diagnosis arrived in the laboratory on
4 Sep 2000. Suspicion of West Nile infection (detection of WN IgG) was
obtained on 5 Sep 2000. On 8 Sep 2000, confirmation was obtained by
detection of specific IgM in sera and West Nile virus detection by RT-PCR
from one brain specimen sent for rabies diagnosis. More samples are
expected and on process.

The "Entente Inter Departementale pour la Demoustication" performed a first
programme of eradication of mosquitoes on 9 Sep 2000 in Lansargues
(Herault) where these 2 confirmed cases were located.

About 20 horses presented [with] encephalitis in the Herault and Gard
departments from the beginning of Aug 2000 according to retrospective
investigation. Most of them died (euthanized).

- --
Herve Zeller
Bernadette Murgue
Centre National de Reference des Arbovirus et Fievres Hemorragiques Virales
Institut Pasteur, 25 rue du Dr Roux
75724 Paris Cedex 15 France
phone 33 (0)1 40 61 30 88
fax 33 (0)1 40 61 31 51
<[EMAIL PROTECTED]>
<[EMAIL PROTECTED]>

[ProMED-mail is grateful to Drs. Zeller and Murque for providing this
information. -Man. Ed. DS]
...............................................ds

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