-Caveat Lector-

AIDS Cat Study Angers Activists

.c The Associated Press

By KATE ROBERTS


COLUMBUS, Ohio (AP) - A researcher's plan to infect 120 cats with
the feline version of HIV and then inject them with
methamphetamine to study the effects has outraged animal rights
activists and is raising questions about the need for the
federally funded study.

Ohio State University professor Michael Podell received a
$355,000 grant from the National Institute on Drug Abuse, part of
the National Institutes of Health, for the first year of what he
expects to be a five-year study costing $1.68 million.

``We want to understand more about HIV and drug abuse in
people,'' said Podell, associate professor of veterinary clinical
sciences. ``One of the ways to do that is to develop an animal
model that has similar characteristics.''

Podell also is interested in the drug's effect on the nervous
system.  Methamphetamine speeds up neurological degeneration -
something Podell says is becoming more of a problem as people
with AIDS are living longer because of improved drug treatments.

Feline immunodeficiency virus and human immunodeficiency virus
have similar effects on the immune and neurological systems of
their respective hosts, he said. Cats also respond to
methamphetamine similar to the way people do. When injected,
methamphetamine is a stimulant that can cause a feeling of
euphoria and hyperactivity. It's also known to cause such
long-term effects as paranoia, hallucinations and strokes.

Peter Wood, a spokesman for People for the Ethical Treatment of
Animals, attacked the study as ``cruel, wasteful and bizarre.''
He argued that HIV and FIV aren't similar enough for the research
to transfer to humans and that the social pressures that would
lead a person to take methamphetamine can't be replicated with
cats.

``It doesn't take a rocket scientist to know meth use will have
an adverse effect on your body so the disease will be promoted
more vigorously,'' Wood said. ``Our limited resources would be
better spent on teaching people how to avoid contracting HIV or
on drug prevention.''

Julio Abreu, spokesman for AIDS Action, a Washington-based AIDS
activist organization, said his group supports studies that aim
to find a cure or vaccine, but to simply establish a control
study in which the results are already known, whether it involves
animals or humans, is a poor use of resources.

``In an era where there's still no cure and no vaccine, I'd hate
for any precious resources to be misguided,'' Abreu said.

Podell defended the study and said the National Institutes of
Health has a set amount of money earmarked for AIDS research.

``The NIH has predetermined how to proportion their funds into
basic science, clinical science and prevention programs,'' he
said. ``The NIH has a very large budget for drug abuse
prevention. There's already a tremendous amount of funding for
that and it's not a situation where they'd take these funds and
use them for a prevention program.''

On the Net:

AIDS Action: http://www.aidsaction.org

National Institutes of Health: http://www.nih.gov

Ohio State University: http://www.osu.edu

People for the Ethical Treatment of Animals: http://www.peta.org


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