-Caveat Lector-

>From UPI,
http://www.vny.com/cf/News/upidetail.cfm?QID=149904

Human cloning within reach, experts say
Friday, 5 January 2001 19:01 (ET)

Human cloning within reach, experts say
By LORI VALIGRA, UPI Science News

NEW YORK, Jan. 5 (UPI) -- Imagine if someone took a scraping of Michael
Jordan's skin cells and cloned a whole team of basketball players who
could win the NCAA championship every year.

Such a scenario has struck both imagination and fear into the debate on
human cloning, sparked after Dolly the lamb was cloned from an adult
sheep in 1997.

But reproductive experts and bioethicists now agree that it is unlikely
that an army of clones will be created. It is more likely, some say,
that cloning will be used by infertile couples wanting to create a
genetically related child or those wishing to clone a lost loved one.

They say the technology already exists to clone a human, and somewhere
in the world right now, someone probably is doing just that, if they
haven't already done it.

That's the contention of an article in the February issue of Wired
magazine, which will hit the newsstands on Jan. 11.

"If cloning has not happened already, it's going to happen very soon,
and the world ought to get over it," said Brian Alexander, author of the
article entitled (You)2 [You-squared].

Alexander told United Press International that his original feeling that
cloning may be freakish and scary was dispelled during his interviews
with experts in human in vitro fertilization and animal reproduction.
Armies of drones won't come into being, he said, because while clones
will carry the same genetic makeup as their parents, they will be quite
different in their behavior and preferences.

"You could clone Michael Jordan and get tall people, but the clones may
not like basketball or even be able to play," he said.

Because of the heated moral and ethical debates on human cloning, work
on the first human clone likely will remain secret, Alexander contends.
Indeed, his article also takes us into the vast underground of anonymous
scientists, religious sects and Web sites like humancloning.org that
support human cloning.

Alexander interviewed an unnamed molecular biologist in the United
States who wants to be the first person to create a human clone. He also
interviewed an unnamed potential client, a businessman living in Western
Europe who lost his son to disease more than a year ago, but who kept
tissues from the body.

The plan is for the scientist and father to fly to an in vitro
fertilization lab in Asia, where the lab's director could potentially
take out the nuclei of eggs obtained from anonymous donors and inject
the son's cells into the eggs to make embryos. Those embryos would be
implanted into five to 10 surrogate mothers in the hope that one of the
eggs would develop into a clone of the client's son.

This is all technically possible, although money and experimentation so
far have kept it from happening, Alexander said. There are very few
regulations on in vitro fertilization. Only a few countries in the
world, including Japan and some European nations but not the United
States, have banned human cloning.

Another group claiming to be working on the first human clone is the
Raelians, a New Age religious group in Quebec that has announced a human
cloning project called Clonaid. Last year the sect said they'd found an
American couple willing to pay $500,000 to clone their dead baby.

This kind of talk remains spine-chilling to many people. But Alexander
contends that such "under-the-radar pro-cloning agitation" is converging
with falling taboos and scientific advances such as DNA microarrays that
can more accurately isolate viable cloned embryos. "Human cloning could
be done tomorrow," he quotes Alan Trounson, an animal cloner and in
vitro fertilization clinician at Australia's Monash University, as
saying.

"All the pieces are out there to do it, so why wouldn't someone do it by
now," Michael Bishop, president of cattle cloning company Infigen Inc.
of DeForest, Wis., told UPI. "I think the public is becoming more
comfortable with the idea of cloning. They are not gasping for air the
way they used to with Dolly."

Author Alexander likens the feelings about human cloning to the
horrified and concerned reactions in 1978 to Louise Brown, the first
test-tube baby, who was born in Britain.

And he points out in his article that the subject of human cloning is no
longer so taboo. Noted scientists, philosophers and authors, including
biologist Edward O. Wilson of Harvard University and novelist Kurt
Vonnegut, have signed the "Declaration in Defense of Cloning and the
Integrity of Scientific Research," a document supporting reasoned
argument on cloning. And Rabbi Michael Broyde of Emery University in
Atlanta wrote an article in the journal Jewish Law about the possible
place of cloning in Jewish tradition.

With discussions of human cloning becoming more open, there are even
some cracks in the ethical wall that has protected use of human embryos,
according to bioethicist George Annas, professor of health law at the
Boston University School of Public Health. Annas does object to human
cloning, but agrees with a recent ruling by Britain's parliament, which
in December approved laws to allow medical research to be conducted
using stem cells derived from human embryos.

But Annas draws the line at letting those cloned embryos be grown into
human beings.

"I don't know why anybody would want to clone a human," Annas told UPI.
"The cloned child will be compared to the original child, and this will
be psychologically damaging."

Cloning technology does have potential value in genetic engineering, or
improving attributes of a person to make him or her smarter or taller,
Annas said, but he objects to that as well. Bishop of Infigen noted that
genetic engineering is not allowed in feed animals.

One thing supporters and detractors of human cloning do agree on is that
only a small number of people will even consider cloning, and they most
likely will be parents with a deceased child or infertile or gay couples
who want a genetically-related child. In addition, there probably will
be people who will try to abuse cloning technology.

"If cloning were made legal tomorrow, it would only appeal to a small
minority of people," said author Alexander. "And there probably will be
abuses. Someone will always want to breed the perfect left-handed relief
pitcher."

Copyright 2000 by United Press International.
All rights reserved.

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