-Caveat Lector-

http://www.armytimes.com/stories/army_story_262259.html


March 23, 2001
New anthrax vaccine tests could start soon


Associated Press

LANSING, Mich. - New tests on the effectiveness and safety of the
anthrax vaccine could begin next week.

The battery of studies - coordinated by the Centers for Disease
Control and Prevention, the lead federal agency charged with
protecting health and safety - could help answer lingering
concerns about the vaccine, which is made solely in the United
States by BioPort Corp. in Lansing.

The CDC studies may help determine if the vaccine can be
effective with fewer doses and how it may best be administered to
military troops to reduce adverse reactions, according to a story
in Friday's Lansing State Journal.

The vaccine is used to combat a deadly biological weapon that
Iraq and up to a dozen other nations possess, according to the
Pentagon.

Anthrax vaccinations were made mandatory for all 2.4 million U.S.
military personnel in 1998, but the program has stalled because
of production problems at BioPort. About 500,000 military
personnel have received at least one dose of the six-shot series.

Military leaders plan to restart the program in early 2002 if the
federal government approves BioPort's vaccine-making process at
renovated labs.

Meanwhile, the vaccine's safety and effectiveness have come under
fire from congressional critics and about 400 military personnel
who have refused to take the drug. The most recent criticism came
Thursday, when Connecticut's attorney general urged the Pentagon
to end the mandatory vaccination program.

The studies that may begin next week won't determine whether
there are long-term health effects associated with the vaccine.
But another branch of the CDC, the National Immunization Program,
will look at some safety issues related to the drug and the
procedures for reporting adverse effects.

The anthrax tests were mandated by Congress last year. The CDC is
seeking an additional $23 million for tests in fiscal year 2002.

CDC committees monitoring tests on animals and humans must OK the
studies before they can begin.

The CDC has hired Battelle Memorial Research Institute to help
conduct the seven-month study of the vaccine's effects on rhesus
monkeys. The project, if approved, will seek to determine if the
vaccine can protect recipients who receive fewer doses than now
required by the Food and Drug Administration and the military.

Troops are now required to receive six shots over an 18-month
period, followed by an annual booster.


Copyright 2001 Army Times Publishing Company. All Rights
Reserved.

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