Package: wnpp
Severity: wishlist
Owner: Steffen Moeller <steffen_moel...@gmx.de>
* Package name : dindel
* URL : https://sites.google.com/site/keesalbers/soft/dindel
* License : GPL-3.0+
Description : find insertions and deletions in biological sequences
The packaging is ready and about to surface on the Debian Med git repository.
Dindel is a program for calling small indels from short-read sequence
data ('next generation sequence data'). It currently is designed to
handle only Illumina data.
.
Dindel requires a BAM file containing the read-alignments as input. It
then extracts candidate indels from the BAM file, and realigns the reads
to candidate haplotypes consisting of these candidate indels. If there
is sufficient evidence for an alternative haplotype to the reference,
it will call an indel.
.
It is possible to test indels discovered with other methods using Dindel,
for instance longer indels obtained through assembly methods. Dindel
will then realign both mapped and unmapped reads to see if the candidate
indel is supported by the reads.
.
Dindel outputs both genotype likelihoods and includes a script to
convert these to a VCF file with indel and SNP calls.
