Another option might be to stop running them from a wheel, as it's clearly not supported by upstream.
- Bug#955414: python3-pip: pip fails to install packages ... Christoph Reiter
- Bug#955414: python3-pip: pip fails to install pack... Scott Kitterman
- Bug#955414: python3-pip: pip fails to install pack... reiter . christoph
- Bug#955414: python3-pip: pip fails to install pack... reiter . christoph