Hi! I extracted one of the failing tests and the corresponding gdb commands so that you can more easily (and quicker) reproduce the issue:
https://salsa.debian.org/fg/rustc-gdb-1031745 instructions are contained within as well. changing the triggering function (multiple_arguments) to either just have the tuple as argument, or making the signature fn multiple_arguments((oo, pp): (isize, isize), (qq, rr): (isize, isize)) { (and adapting the call accordingly) makes the problem go away. just having multiple_arguments with the call as standalone test case also doesn't trigger the issue.