Courtesy of Steve Block Volume II, Issue 2 17 Sizing Up Nanotechnology Block, is that
"if we are ever to build machines which are in any way based on biological
structures, then we will have to learn about how real biological systems function."
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To study single molecules, Block has pioneered the use of optical tweezers, tiny laser-based "tractor beams"
that produce miniscule piconewton forces to drag around molecules and allow measurements of displacements on the order
of a nanometer. "You can stop and stall molecules, w follow their motion. Recently, we've studied the backtracking
of RNA polymerase: when it makes a mistake, it can actually back up by five bases, scoop off the wrong thing and start
again," says Block. While biological nanotechnology "hasn't even arrived at its infancy yet," says
Block, "biological nanoscience is a very exciting place to be right now, because the techniques now exist to truly
study proteins, and we're learning so much about them."
All this from pencil lead: "graphite is a very old material, but take a tiny tube of
graphite and it has totally different properties, says Dai. "That's what nanotech is all
about."
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