Hi, I managed to build the latest upstream version of sra-toolkit 2.7.0. I made sure that the vschema files will be found but since I've got
$ latf-load --quality PHRED_33 -o test /usr/share/doc/python-biopython-doc/Tests/Quality/sanger_93.fastq 2016-09-01T13:27:09 latf-load.2.7 warn: file="/usr/share/doc/python-biopython-doc/Tests/Quality/sanger_93.fastq" 2016-09-01T13:27:09 latf-load.2.7 warn: /usr/share/doc/python-biopython-doc/Tests/Quality/sanger_93.fastq:1:12:syntax error, unexpected fqWS 2016-09-01T13:27:09 latf-load.2.7 warn: The file contained no records that were processed. 2016-09-01T13:27:09 latf-load.2.7 err: libs/kproc/queue.c:356:KQueuePop: data empty while reading file within alignment module - accession="test" errors="1" status="failure" 2016-09-01T13:27:09 latf-load.2.7 err: libs/kproc/queue.c:356:KQueuePop: data empty while reading file within alignment module - load failed I reported the issue upstream as issue #39 [1]. Kind regards Andreas. [1] https://github.com/ncbi/sra-tools/issues/39 -- http://fam-tille.de