Hi,

it seems there was a racing condition with upstream. :-)

    https://github.com/lh3/bwa/pull/141

It would be great if somebody could even upload a fixed package.

Kind regards

      Andreas.

On Mon, Jul 03, 2017 at 07:09:55PM -0700, Nadiya Sitdykova wrote:
> Hello,
> 
> Fabian, thanks a lot, it was enlightening. I added those patches as is.
> 
> Regards, Nadiya
> 
> On Sat, Jul 1, 2017 at 4:06 AM, Fabian Klötzl <kloe...@evolbio.mpg.de>
> wrote:
> 
> > Hi,
> >
> > I much prefer an interesting coding challenge to cleaning out my flat,
> > so I tackled this problem.
> >
> > On 01.07.2017 00:04, Nadiya Sitdykova wrote:
> > >
> > > 2) negative argument for malloc size
> > > ==10017== Thread 13:
> > > ==10017== Argument 'size' of function malloc has a fishy (possibly
> > > negative) value: -9223372036854775657
> > > ==10017==    at 0x4C2BBAF: malloc (vg_replace_malloc.c:299)
> > > ==10017==    by 0x12E34A: bsw2_pair1 (bwtsw2_pair.c:123)
> > > ==10017==    by 0x12EC37: bsw2_pair (bwtsw2_pair.c:193)
> > > ==10017==    by 0x127B4E: bsw2_aln_core (bwtsw2_aux.c:621)
> > > ==10017==    by 0x127E90: worker (bwtsw2_aux.c:660)
> > > ==10017==    by 0x535D493: start_thread (pthread_create.c:333)
> > >
> > > Thanks to debug output I knew that this happens when l_mseq = 149, end =
> > > 0, beg = 1
> >
> > end is not 0, but a *very* small number. But that is only the symptom of
> > an issue earlier on.
> >
> > In bsw2_stat some statistics of the given data are computed, which are
> > then used to calculate beg and end in bsw2_pair1, the function with the
> > broken malloc. The computed statistics are avg and std. However, only
> > values within certain boundaries are used to compute the avg. If none of
> > the input values fall within that interval it all boils down to avg =
> > 0/0 = NaN. This then screws up any downstream computation. A
> > straightforward patch is attached to this mail.
> >
> > While I was at it, I also created a patch for the malloc wrapper: size_t
> > is unsigned. (Technically, the valgrind message given above is also wrong.)
> >
> > Feel free to modify and forward at you leisure.
> >
> > Best,
> > Fabian
> >
> >

-- 
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