Hi, I tried to narrow down what broke clustalo on mipsel.
The test from 1.2.4-5 passes with the binary in buster, but not when rebuilding it in buster. gcc versions: 7: works 8: broken 9: broken 10: broken clustalo in buster was built with gcc 7, a rebuild with the gcc 8 now in buster would result in a broken binary. Rebuilding with gcc 8 with -O0 does not work around the problem, this is unlikely to be the the common case of optimization changes breaking buggy code. What does fix the problem is disabling OpenMP. I suspect OpenMP is somehow broken in gcc >= 8 on mipsel. Below is a workaround patch (lower performance of clustalo on mipsel shouldn't be a major problem). cu Adrian --- clustalo-1.2.4/debian/rules 2020-04-14 12:19:44.000000000 +0300 +++ clustalo-1.2.4/debian/rules 2020-04-14 12:19:44.000000000 +0300 @@ -9,6 +9,11 @@ %: dh $@ +ifneq (,$(filter $(DEB_HOST_ARCH), mipsel)) +override_dh_auto_configure: + dh_auto_configure -- --without-openmp +endif + override_dh_auto_build-indep: # nothing to do here