I have used it on client machines for the past 6 months and also find it
equal to Norton Corp except for one thing. It handles mail clients
differently in that it does not scan email as they come in but instead seems
to scan it only when you attempt to read it.
Norton Corp seemed to catch the viruses as soon as the mail was popped and
worked with exchange client very well also.
Only if you're using Microsoft clients. If you're using something like Eudora, which writes the attachments to disk as soon as they are received (and is also immune to attacks or exploits targeted at Outlook/Outlook Express), it alerts on the viruses immediately.