On 08/05/13 05:33 PM, Yuqing Xiong wrote:
> Hi, Sebastien,
>
> I am a researcher in computational biology, and studying your papers,"Ray: 
> Simultaneous Assembly of Reads from a Mix of High-Throughput Sequencing 
> Technologies"
>and "Ray Meta: scalable de novo metagenome assembly and profiling". The former 
>is about non metagenome assembly and the latter is about metagenome assembly.
>When the quality of the assemblies are assessed, the assembly metrics at the 
>two paper are different, the chimeric contig, mismatch, and indel are included
>at the former, but not inculded at the latter. I think that the cause is from 
>binning, that is, it is not known that a contig belongs to which species in 
>metagenome assembly.
>
> My question is that why you don't confirm every contig belong to which 
> species, and then assess the quality of assembly of every contig in the 
> second paper?
>

We actually verified the assembly quality in our paper [1] for the 100-genome 
metagenome and for the 1000-genome
metagenome (in the Results section).

> Best regards,
>
> --Yuqing


---
[1] http://genomebiology.com/2012/13/12/R122

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