I can confirm we are also experinecing this on both 6.06 LTS and 6.10, have also tried with rdesktop 1.5 compiled from source. This bug affects many of our users 5-6 times during the working day.
Have been able to "unfreeze" any of their machines remotely by running killall -9 gnome-screensaver which led me to find this bug on launchpad. -- mouse issue screensaver + rdesktop https://launchpad.net/bugs/70075 -- desktop-bugs mailing list desktop-bugs@lists.ubuntu.com https://lists.ubuntu.com/mailman/listinfo/desktop-bugs