Hello all. Has anybody tried this I wonder? I'm about to investigate it for accessibility.
I don't have the Macintosh version, but the Windows version uses a whole lot of drag and drop operations for interface dealing with editing tags. From this perspective, Acrobat is a page layout program, so I am not sure how they might fix this. But the apparent accessibility depends on what you are trying to get out of. If you want to use Acrobat to produce well structured PDFs from well structured Word files, then you will find Acrobat to be compatible with your screen reader. If you want to use Acrobat to repair PDFs, which is my primary use of the software, then you are out of luck if you need to use a screen reader.
