May by
-with-postgres-libraries=/opt/local/lib/postgresql
Or -with-postgres-libraries=/opt/local/lib
And why not using psycopg2?
It is beta, but i not has a proplem with it. Just edit django's
postgresql module to import psycopg2 and comment register-type
(psycopg2 use datetime.datetime internally - not mxDateTime)- Re: psycopg - PostGreSQL libraries (not) missing Sokolov Yura

