We run CentOS on our servers and use virtualenv for each of our various django 
projects (multiple projects on one server), we haven't had any issues, but we 
use fastcgi between the web server and django.

On May 23, 2011, at 7:00 PM, John Crawford wrote:

> I'd like to know what kind of experience people have had, in using
> virtualenv (to run a particular version of Python on a VPS) with
> Django, and related packages? Not *just* Django (and Python), I'm
> fairly sure that will work, but all the other bits and pieces that
> tend to be required, like mod_wsgi, or mysqldb_python, and so on?
> 
> Is virtualenv really effective, or does it turn out to be a nightmare
> to get everything working correctly? I've been looking around the web
> (particularly StackOverflow), and it like more like a nightmare. :(
> 
> The VPS I am using, turns out to run on CentOS, which uses Python 2.4
> for everything, alas. So either I downgrade all my existing 2.6 code
> to 2.4, or I install 2.6 on the VPS without breaking it, which would
> require virtualenv. (Or changing hosting, which I'm also seriously
> considering...)
> 
> John C>
> 
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