You have not really provided an argument, though.

Programmers generally do not just do a thing for the sake of doing the
thing, even if it's a "neat" thing. They do a thing because they have a
need for that thing. We turn to things that can speed up our programs once
we have determined that some part of our program is not running fast enough
to meet some specific goal. Until we know that we have a problem, we don't
try to reach for a solution.

Django can, as the other reply mentioned, run on PyPy, which uses a nice
JIT compiler. If you have no specific goal in mind other than "I heard
about JIT and want to use it", then run Django on PyPy. If you want to have
web applications written in C, write your web applications in C.

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