Selamat menunaikan Ibadah puasa, mohon maaf lahir bathin,
Dengan berpuasa insya allah tubuh akan semakin sehat, terlbeih lagi hubungannya 
dengan kesehatan jantung dan pembuluh darah kita....olehnya...
Sembari menunggu beduk berbuka puasa, terkirim bacaan ringan tentang:
�
"Pengobatan terkini yang berhubungan dengan penyakit jantung secara Gene-tika 
yang kebetulan merupakan disertasi kami dalam menyelsaikan pendidikan PhD di 
Niigata University" dapat dinikmati via meng-klik alamat berikut:
Gene Therapy (Dissertation)     May 28, '08 2:04 AM
for everyone

Functional Impact of Altered Charge and/or Size of Amino Acid Residue at the 
Selectivity Filter of KCNQ1 Potassium Channel: Insight into Gene Therapy for 
Severe Long QT Phenotype

By TARUNA IKRAR, MD

The discovery of pathogenic mutations primarily in genes encoding cardiac ion 
channel protein underlying the primary cardiac arrhythmia syndromes has had a 
remarkable impact on the management of disorders, especially in patients with 
the long QT syndrome. Together, our data and previous report could indicate 
that the clinical phenotype is not only dependent on the location, but also the 
type of mutant amino acid residues (imposed by their size and charge for 
instance). These new findings can enrich the studies on channel properties and 
functions, with a new perspective related to the strategies for diagnostic, 
gene specific risk stratification, and gene therapy directed to individual 
hereditary diseases of Long QT Syndrome

Jika ada yang membutuhkan draft lengkap (PDF), dengan hormat akan di-kirim via 
japri.
�
Billahit taufiq wal hidayah
wassalamu alaikum wr. wb.
Taruna Ikrar




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