--- In dokter_umum@yahoogroups.com, "Dr.(Naturopathy) Ir. Donny Hosea MBA. PhD." <[EMAIL PROTECTED]> wrote: > > Hello, > Barangkali ini membantu? > Bacalah semua samapi akirnya. >
Hello juga Dok. dan terimakasih atas kiriman artikelnya. Terkait tulisan dibawah ini. Apah yah maksud dari : 1. Reaksi anaphylactic 2. hyperpigmentation 3. Resep yang diberikan oleh dokter kepada saya adalah EtoxySclero type yang 2 %. dimana kandungan Polidacanol nya 40 mg, dan etanol 0.10 ml per ampul. Dokternya meminta disediakan 2 ampul. Kira2 cukup aman ngak yah komposisi seperti itu. PS : Sorry banyak nanya. Soalnya menerjemahkan bahasa inggrisnya saja saya sudah kesulitan, apalagi ditambah istilah istilah kedokteran lagi :) _/*Etoxisclerol*/_^® , Sotrauerix^® , Laureth 9^® ). All commercially available formulations contain some small quantity of ethanol. The drug was originally developed and marketed in the 1950s under the name Sch 600^® as a non-amide, non-ester local anaesthetic that was useful for injected local anaesthesia as well as for epidural anaesthesia and for topical mucosal anaesthesia. It was first used as a sclerosing agent in Germany in the 1960s, and was quickly adopted for that use in most countries. The drug is not yet approved by the FDA for sale in the United States as a sclerosing agent, but is nonetheless widely used because it offers certain advantages over many other available drugs. As a local anaesthetic, Polidocanol is painless upon injection. It does not produce necrosis if injected intradermally, and has been reported to have a very low incidence of allergic reactions. The drug has been intensely studied and extremely well characterized, and has a high therapeutic index. The LD50 in rabbits is 200 mg/kg (approximately 5 times greater than that of novocaine), and the LD50 in mice is even greater, at 1200 mg/kg. *For human use the German manufacturer of polidocanol recommends a maximum daily dose of 2 mg per kg, although at least one author has reported the routine use of much higher doses. For all its advantages, polidocanol is not without problems as a sclerosant. Occasional anaphylactic reactions have been reported. In some patients it may produce hyperpigmentation, although to a lesser extent than many other agents. Telangiectatic matting after sclerotherapy with polidocanol is as common as with any other agent.*
