> Basically I want the server to check if the message being sent is encrypted 
> with OpenGPG and either proceed or reject the message based on that criteria.


Postfix is your submission service so i think best to look that direction. If 
there is a header you can check for (if the header exist then allow sending) 
then postfix has header checks regexp/pcre that would be simple enough to setup.

On the more complex side, postfix also supports policy servers you can write as 
a script (php, perl, python, etc) or you can go full on milter.


http://www.postfix.org/header_checks.5.html
http://www.postfix.org/SMTPD_POLICY_README.html
http://www.postfix.org/postconf.5.html#non_smtpd_milters

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