I think there is a paper by Jim Gauderman on this topic from a couple of years ago. Maybe in Genetic Epidemiology, but I am not sure about this. If I remember, power to detect such an interaction was horrid for realistic sample sizes. ************************************************************************ Ellen M. Wijsman COURIER DELIVERY ADDRESS ONLY: Research Professor Ellen M. Wijsman Div. of Medical Genetics and 1914 N 34th St., suite 209 Dept. Biostatistics Seattle, WA 98103 BOX 357720, University of Washington (Note: Use this address Seattle, WA 98195-7720 EXACTLY as given above, and phone: (206) 543-8987 use ONLY for courier delivery!!!) fax: (206) 616-1973 email: [EMAIL PROTECTED] web page: http://www.biostat.washington.edu/biostat/faculty/ewijsman ************************************************************************* On Wed, 7 Feb 2001, James Cui wrote: > Dear all: > > Is anybody aware of a sample size or power calculation for a continuous > trait in gene-gene or gene-environment interaction in the literature? > > Thanks a lot, > Jisheng. > > > ____________________________________________________ > > Jisheng Cui, Ph.D > Research Fellow > Centre for Genetic Epidemiology, > School of Population Health, > University of Melbourne, > 200 Berkeley Street, Carlton, > Victoria 3053, Australia > Tel: +613 8344-4989 Fax: +613 9347-6136 > mailto:[EMAIL PROTECTED], > http://ariel.unimelb.edu.au/~jisc/ > ____________________________________________________ > > > > > ================================================================= Instructions for joining and leaving this list and remarks about the problem of INAPPROPRIATE MESSAGES are available at http://jse.stat.ncsu.edu/ =================================================================